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姓 名:
陈航榕
性    别:
专家类别:
研究员;杰青;百千万人才
学 历:
博士研究生
电 话:
021-52412706;13524670619
传 真:
021-52413122
电子邮件:
hrchen@mail.sic.ac.cn
个人主页:
邮政编码:
200050
通讯地址:
上海市定西路1295号2#706室

简历:

  陈航榕:女,博士,研究员,博士生导师;2012年国家杰出青年科学基金获得者,2015年荣获政府特殊津贴。2001年7月毕业于中国科学院上海硅酸盐研究所获博士学位;2003年6-12月英国曼彻斯特大学材料研究中心访问学者;2014年11月—2015年2月澳大利亚昆士兰大学化工学院高访研修。高性能陶瓷和超微结构国家重点实验室副主任,主要从事纳米介孔结构材料、纳米生物材料、纳米催化材料等研究;作为负责人先后主持承担了包括国家863、973、国家科技支撑计划、国家自然科学基金、中科院科技创新团队、上海市纳米专项、技术标准专项、启明星(跟踪)计划等科研项目;作为项目骨干承担完成了包括973、院方向性创新项目、国家自然基金重点项目、上海市重大基础项目等。

  在Angew. Chem. Int. Ed.,Adv.Mater., Adv.Func.Mater., ACS Nano,Biomaterials,等国际著名期刊上发表SCI学术论文200余篇;他引总计7000余次,h因子47,获得20余项国家发明专利授权。荣获上国家自然科学二等奖1项(2011,排名第二);上海市自然科学一等奖2项(2008,排名第二;2014年,排名第五);上海市标准化优秀技术成果二等奖1项(2011,排名第一)。入选国家百千万人才工程“有突出贡献中青年专家”(2013年度);上海市优秀学术带头人计划(2014年度);中国科学院朱李月华优秀研究生导师(2014年度);科技部创新人才推进计划中青年科技创新领军人才(2014年度);第二批国家“万人计划”科技创新领军人才(2016);第五届中国科学院“十大杰出妇女”(2017)等多项荣誉与奖励。担任福州大学、南京工业大学兼职教授;“无机材料学报”、“Scientific Reports”编委;中国超声医学工程学会超声分子影像学专业委员会常务委员;中国生物医学工程学会生物医学光子学分会副秘书长等职。

  主要研究方向:

  (1)无机基纳米生物材料及其肿瘤诊断与协同治疗研究

  (2)无机纳米催化材料设计合成与性能研究

  (3)多级孔复合纳米材料及其柴油车尾气催化净化研究

  主要科研项目(负责人):

  1、上海市国际合作项目:“新型碳基复合纳米电催化剂的设计制备及电解水研究”,编号:16520710200,2016.7-2019.6

  2、国家重大科技基础研究发展计划(973)“半封闭空间机动车排放污染物治理的关键技术”之课题2“NOx的常温吸附/催化氧化/碱吸收过程与纳米材料的设计合成与性能”课题编号:2013CB933202(2013.1-2017.8)

  3、上海市优秀学术带头人计划:“多功能纳米超声诊疗剂研究”编号:14XD1403800, 2014.7.1-2017.6.30

  4、国家万人计划领军人才项目,2017.1—2019.12

  5、国家杰出青年科学基金项目, “介孔结构纳米材料与性能研究”,编号:51225202,2013,1—2016,12

  近5年重要论文发表(均为通讯作者):

  1. Juan Mou, Tianquan Lin, Fuqiang Huang, Jianlin Shi and Hangrong Chen*, A New Green Titania with Enhanced NIR Absorption for Mitochondria-Targeted Cancer Therapy, Theranostics, 2017; 7(6): 1531-1542. 

  2. Qianru Li, Gang Wan, Han Zhao, Linyu Pan, Ning Wang, Wanpeng Zhao, Xiaoxia Zhou, Xiangzhi Cui and Hangrong Chen*Nitrogen-doped Carbon Vesicles with Dual Iron-based Sites for Efficient Oxygen ReductionChemSusChem, 2017,10,499-505. 

  3. Xiaojun Cai, Wei Gao, Linlin Zhang, Ming Ma, Tianzhi Liu, Wenxian Du, Yuanyi Zheng, Hangrong Chen*, and Jianlin Shi, Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy, ACS Nano, 2016, 10,11115-11126. 

  4. Kun Zhang, Huixiong Xu, Xiaoqing Jia, Yu Chen, Ming Ma, Liping Sun, and Hangrong Chen*, Ultrasound-Triggered Nitric Oxide Release Platform Based on Energy Transformation for Targeted Inhibition of Pancreatic Tumor, ACS Nano, 2016, 10,10816-10828. 

  5. Zhou, XX; Chen, LS; Wan, G; Chen, Y; Kong, QL; Chen, HR*; Shi, JL*, Low Pt-Loaded Mesoporous Sodium Germanate as a High-Performance Electrocatalyst for the Oxygen Reduction Reaction, ChemSusChem, 2016,9(17), 2337-2342.  

  6. Mou, J; Lin, TQ; Huang, FQ; Chen, HR* ; Shi, JL*, Black titania-based theranostic nanoplatform for single NIR laser induced dual-modal imaging-guided PTT/PDTBiomaterials, 2016,84,13-24.  

  7. Yu, LD; Chen, Y*; Wu, MY; Cai, XJ; Yao, HL; Zhang, LL; Chen, HR*; Shi, JL*"Manganese Extraction" Strategy Enables Tumor-Sensitive Biodegradability and Theranostics of NanoparticlesJ.Am.Chem.Soc., 2016, 138(31), 9881-9894. 

  8. Zhang, K; Li, P; He, YP; Bo, XW; Li, XL; Li, DD; Chen, HR*; Xu, HX*, Synergistic Retention Strategy of RGD Active Targeting and Radiofrequency-enhanced Permeability for Intensified RF&Chemotherapy Synergistic Tumor Treatment, Biomaterials, 2016,99,34-46. 

  9. Ma, MYan, F; Yao, MHWei, ZJ; Zhou, DL; Yao, HL; Zheng, HR*; Chen, HR*, Shi, JL, Template-Free Synthesis of Hollow/Porous Organosilica-Fe3O4 Hybrid Nanocapsules toward Magnetic Resonance Imaging-Guided High-Intensity Focused Ultrasound TherapyACS Applied Materials Interfaces, 2016,8(44),29986-29996.  

  10. Xie, ZG; Zhou, XX*; Wu, HX; Chen, LS; Zhao, H; Liu, Y; Pan, LY; Chen, HR*, One-pot hydrothermal synthesis of CuBi co-doped mesoporous zeolite Beta for the removal of NOx by selective catalytic reduction with ammonia. Sci. Rep. 20166, 30132. 

  11. Wan, G; Ma, M; Jia, A; Chen, LS; Chen, Y; Cui, XZ; Chen, HR*; Shi, JL, 3D hierarchical assembly of optimized heterogeneous carbon nanosheets for highly efficient electrocatalysis, J. Mater. Chem. A, 2016, 4(30), 11625-11629. 

  12. Shige Wang, Xiang Li, Yu Chen, Xiaojun Cai, Heliang Yao, Wei Gao, Yuanyi Zheng, Xiao An*, Jianlin Shi and Hangrong Chen*, A Facile One-Pot Synthesis of a Two-Dimensional MoS2/Bi2S3 Composite Theranostic Nanosystem for Multi-Modality Tumor Imaging and Therapy. Advanced Materials. 2015, 27(17),2775 

  13. Wang SG, Li K, Chen Y, Chen HR*, Ma M, Feng JW, Jianlin Shi* et al. Biocompatible PEGylated MoS2 nanosheets: Controllable bottom-up synthesis and highly efficient photothermal regression of tumor. Biomaterials. 2015;39:206-17. 

  14. Cai XJ, Jia XQ, Gao W, Zhang K, Ma M, Wang SG, Zheng YY, Shi JL*, Chen HR*, A Versatile Nanotheranostic Agent for Efficient Dual-Mode Imaging Guided Synergistic Chemo-Thermal Tumor Therapy. Advanced Functional Materials, 2015, 25172520-2529. 

  15. Zhang K, Chen HR*, Guo XS, Zhang D, Zheng YY, Zheng HR, Jianlin Shi*, et al. Double-scattering/reflection in a Single Nanoparticle for Intensified Ultrasound Imaging. Scientific Reports. 2015;5,8766. 

  16. Mou J, Li P, Liu C, Xu H, Song L, Wang J, Chen HR*, Jianlin Shi*et al. Ultrasmall Cu2-xS Nanodots for Highly Efficient Photoacoustic Imaging-Guided Photothermal Therapy. Small. 2015,11(19),2275-2283. 

  17. Ma M, Huang Y, Chen HR*, Jia XQ, Wang SG, Wang ZZ, Jianlin Shi* et al. Bi2S3-embedded mesoporous silica nanoparticles for efficient drug delivery and interstitial radiotherapy sensitization. Biomaterials. 2015;37:447-55. 

  18. Chen Y, Chen HR*, Shi JL*. Nanobiotechnology Promotes Noninvasive High-Intensity Focused Ultrasound Cancer Surgery. Advanced Healthcare Materials, 2015;4(1),158-165. 

  19. Jin Wang, Jinzhen Zhu, Xiaoxia Zhou, Yanyan Du, Weimin Huang, Jianjun Liu*, Wenqing Zhang, Jianlin Shi and Hangrong Chen*, Nanoflower-like weak crystallization manganese oxide for efficient removal of low-concentration NO at room temperature,Journal of Material Chemistry A, 2015, 3(14),7631-7638. 

  20. Xiaoxia Zhou, Hangrong Chen,* Guobin Zhang, Jin Wang, Zhiguo Xie, Zile Hua, Lingxia Zhang and Jianlin Shi*, Cu/Mn co-loaded hierarchically porous zeolite beta:a highly efficient synergetic catalyst for soot oxidation, Journal of Material Chemistry A, 2015, 3(18),9745-9753. 

  21. J.Mou, C.Liu,P.Li, Y.Chen, H.Xu, C.Wei, L.Song*, J.Shi, H.Chen*, A facile synthesis of versatile Cu2-xS nanoprobe for enhanced MRI and infrared thermal/photoacoustic multimodal imaging, Biomaterials, 2015,57,12-21. 

  22. Cai XJ, et al., A Prussian blue-based Core-shell Hollow-structured Mesoporous Nanoparticle as a Smart Theranostic Agent with Ultrahigh pH-responsive Longitudinal Relaxivity, Adv.Mater.2015,27(41), 6382 

  23. Zhang K, et al.,CO2 bubbling-based ‘Nanobomb’ System for TargetedlySuppressing Panc-1 Pancreatic Tumor via Low IntensityUltrasound-activated Inertial Cavitation, Theranostics, 2015, 5 (11), 1291 

  24. Shige Wang, Yu Chen,* Xiang Li, Wei Gao, Linlin Zhang, Jun Liu, Yuanyi Zheng ,Hangrong Chen,* and Jianlin Shi, Injectable 2D MoS2 -Integrated Drug Delivering Implantfor Highly Effi cient NIR-Triggered Synergistic TumorHyperthermia,Adv.Mater.2015,27,7117–7122. 

  25. Zhang K, Chen HR*, Zhou XX, Gong Y, Zhang GB, Wang X, Shi JL*, et al. Unconventional Pd nanoparticles' growth induced by a competitive effect between temperature-dependent coordination and reduction of grafted amino ligands for Heck reaction. J Mater Chem A. 2014;2:1515-23. 

  26. Zhang K, Chen HR*, Li FQ, Wang Q, Zheng SG, Xu HX, Shi JL* et al. A continuous tri-phase transition effect for HIFU-mediated intravenous drug delivery. Biomaterials. 2014;35:5875-85. 

  27. Yao MH, Ma M, Chen Y, Jia XQ, Xu G, Xu HX, Chen HR*, Wu R*, Multifunctional Bi2S3/PLGA nanocapsule for combined HIFU/radiation therapy. Biomaterials. 2014;35:8197-205. 

  28. Wang X, Chen HR*, Zhang K, Ma M, Li FQ, Zeng DP, Shi JL* et al. An Intelligent Nanotheranostic Agent for Targeting, Redox-Responsive Ultrasound Imaging, and Imaging GuidedHigh- Intensity Focused Ultrasound Synergistic Therapy. Small. 2014;10:1403-11. 

  29. Ma M, Xu HX, Chen HR*, Jia XQ, Zhang K, Wang Q, Shi JL* et al. A Drug-Perfluorocarbon Nanoemulsion with an Ultrathin Silica Coating for the Synergistic Effect of Chemotherapy and Ablation by High-Intensity Focused Ultrasound. Advanced Materials. 2014;26:7378-85. 

  30. Chen Y, Xu PF, Wu MY, Meng QS, Chen HR*, Shu Z, Shi JL* et al. Colloidal RBC-Shaped, Hydrophilic, and Hollow Mesoporous Carbon Nanocapsules for Highly Efficient Biomedical Engineering. Advanced Materials. 2014;26:4294-301. 

  31. Chen Y, Xu PF, Shu Z, Wu MY, Wang LZ, Zhang SJ, Chen HR*, Jianlin Shi* et al. Multifunctional Graphene Oxide-based Triple Stimuli-Responsive Nanotheranostics. Advanced Functional Materials. 2014;24:4386-96. 

  32. Chen Y, Jiang L, Wang RH, Lu M, Zhang QX, Zhou Y, Chen HR*, Zheng YI* et al. Injectable Smart Phase-Transformation Implants for Highly Efficient In Vivo Magnetic-Hyperthermia Regression of Tumors. Advanced Materials. 2014;26:7468-73. 

  33. Yu Chen, Hangrong Chen* and Jianlin Shi*, Construction of Homogenous/Heterogeneous Hollow Mesoporous Silica Nanostructures by Silica-Etching Chemistry: Principles, Synthesis,and Applications, Accounts of Chemical Research, 2014,47,125-137. 

  34. Kun Zhang, Hangrong Chen,* Xiaoxia Zhou, Yun Gong, Guobin Zhang, Xia Wang, Yu Chen and Jianlin Shi*, Unconventional Pd Nanoparticles’ Growth Induced by Competitive Effect between Temperature-dependent Coordination and Reduction of Grafted Amino Ligands for Heck Reaction, Journal of Materials Chemistry A, 2014, 2 (5), 1515 – 1523.  

  35. Xiaoxia Zhou, Hangrong Chen*, Yuanyuan Sun, Kun Zhang, Xiangqian Fan, Yan Zhu,Yu Chen, Guiju Tao, Jianlin Shi*, Highly efficient light-induced hydrogen evolution from a stablePt/CdS NPs-co-loaded hierarchically porous zeolite beta, Applied Catalysis B: Environmental, 2014,152–153,271–279.  

  36. Xia wang, Hangrong Chen,* Kun Zhang, Ming Ma, Faqi Li, Deping Zeng, Shuguang Zheng, Yu Chen, Lixin Jiang, Huixiong Xu and Jianlin Shi* An intelligent nanotheranostic agent for targeting, redox-responsive ultrasound imaging and imaging-guided HIFU synergistic therapy, Small, 2014;10:1403-11. 

  37. Yu Chen, Hangrong Chen* and Jianlin Shi*, In Vivo Bio-Safety Evaluations and Diagnostic/Therapeutic Applications of Chemically Designed Mesoporous Silica Nanoparticles., Advanced  Materials, 2013, 25, 3144–3176. 

  38. Yu Chen, PengfeiXu, Hangrong Chen*, Yongsheng Li, Wenbo Bu, Zhu Shu, Yaping Li, Jiamin Zhang, Lingxia Zhang, Limin Pan, Xiangzhi Cui, ZileHua, Jin Wang, Linlin Zhang and Jianlin Shi*, Colloidal HPMO Nanoparticles: Silica-Etching Chemistry Tailoring, Topological Transformation, and Nano-Biomedical Applications, Advanced  Materials, 2013, 25, 3100–3105. 

  39. Xia Wang, Hangrong Chen*, Yuanyi Zheng, Ming Ma, Jianlin Shi*, et al, Au-nanoparticle coated mesoporous silica nanocapsule-based multifunctional platform for ultrasound mediated imaging, cytoclasis and tumor ablation,  Biomaterials, 2013, 34, 2057-2068.  

  40. Xiaoxia Zhou, Hangrong Chen*, Yan Zhu, Yudian Song, Yu Chen, Yongxia Wang, Yun Gong, Guobin Zhang, Zhu Shu, Xiangzhi Cui, Jinjin Zhao and Jianlin Shi*. Dual Mesoporous-Structured ZSM-5 Zeolite with Highly b-Axis-Oriented Large Mesopore Channels for the Production of Benzoin Ethyl Ether, Chemistry-A European Journal, 2013;19:10017-23. 

  41. Xia Wang, Hangrong Chen*, Yu Chen, Ming Ma, Kun Zhang, Faqi Li, Yuanyi Zheng, Deping Zeng, Qi Wang, Jianlin Shi*, Perfluorohexane-Encapsulated Mesoporous Silica Nanocapsules as a Highly Efficient HIFU Synergistic Agent, Advanced Materials, 2012, 24(6),785-791.  

  42. Ming Ma, Hangrong Chen*, Yu Chen, Xia Wang, Feng Chen, Xiangzhi Cui, Jianlin Shi*,  Au Capped Magnetic Core/Mesoporous Silica Shell Nanoparticles For Combined Photothermo-/Chemo- Therapy And Multimodal Imaging, Biomaterials, 2012, 33, 989-998.   

  43. Yu Chen, Qi Yin,Shengjian Zhang, Hangrong Chen*, Yuanyi Zheng, Yang Sun, Jianlin Shi*, Manganese oxide-based multifunctionalized mesoporous silica nanoparticles for pH-responsive MRI, ultrasonography and circumvention of MDR in cancer cellsBiomaterials, 2012,33,7126-7137.  

  44. Ming Ma, Hangrong Chen,* Yu Chen, Kun Zhang, Xia Wang, Xiangzhi Cui and Jianlin Shi*, Hyaluronic acid-conjugated mesoporous silica nanoparticles: excellent colloidal dispersity in physiological fluids and targeting efficacy, Journal of Materials Chemistry, 2012, 22 (12), 5615 – 5621.  

  45. Yu Chen, Yu Gao, Hangrong Chen*, Deping Zeng, Yaping Li, Yuanyi Zheng, Faqi Li, Xia Wang, Feng Chen, Qianjun He, Linlin Zhang and Jianlin Shi*, Engineering “Inorganic Nanoemulsion/Nanoliposome” by Fluoride-Silica Chemistry for Efficient Delivery/Co-delivery of Hydrophobic Agents, Advanced Functional Materials, 2012, 22,1586.  

  46. Yu Chen, Hangrong Chen*, Shengjian Zhang, Feng Chen, Shikuan Sun, Qianjun He, Ming Ma, Xia Wang, Huixia Wu, Lingxia Zhang and Jianlin Shi*, Structure-Property Relationships in Manganese oxide - Mesoporous Silica Nanoparticles Used for T1-Weighted MRI and Simultaneous Anticancer Drug Delivery, Biomaterials, 2012, 33(7),2388-2398.   

  47. Kun Zhang, Hangrong Chen* ,Yuanyi Zheng,Yu Chen,Ming Ma,Xia Wang, Lijun Wang,Deping Zeng and Jianlin Shi* A facile in situ hydrophobic layer protected selective etching strategy for the synchronous synthesis/modification of hollow or rattle-type silica nanoconstructs, Journal of Materials Chemistry2012,22, 12553-12561 

  48. Yu Chen, Hangrong Chen*, Yang Sun, Yuanyi Zheng, Deping Zeng, Faqi Li, Shengjian Zhang, Xia Wang, Kun Zhang, Ming Ma, Qianjun He, Linlin Zhang and Jianlin Shi*, Multifunctional Mesoporous Composite Nanocapsules for Highly Efficient MRI-Guided High Intensity Focused Ultrasound Cancer Surgery, Angew. Chem. Int. Ed., 2011, 50,12505-12509.  

  49. Yu Chen, Hangrong Chen*, Shengjian Zhang, Feng Chen, Lingxia Zhang, Jiamin Zhang, Min Zhu, Huixia Wu, Jingwei Feng and Jianlin Shi*, Multifunctional Mesoporous Nanoellipsoids for Biological Bimodal Imaging and Magnetically Targeted Delivery of Anticancer Drugs, Advanced Functional Materials, 2011, 21, 270-278.   

  50. Yu Chen, Chen Chu, Yuchuan Zhou, Hangrong Chen*, Feng Chen, Qianjun He, Yonglian Zhang, Linlin Zhang and Jianlin Shi, Reversible Pore-Structure Evolution in Hollow Silica Nanocapsules: Large Pores for siRNA Delivery and Nanoparticle Collecting, Small, 2011, 7, 2935-2944.

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