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姓 名:
常江
性    别:
专家类别:
研究员
学 历:
博士研究生
电 话:
021-52412804
传 真:
021-52413903
电子邮件:
jchang@mail.sic.ac.cn
个人主页:
邮政编码:
200050
通讯地址:
上海市定西路1295号

简历:

  常江:中科院上海硅酸盐研究所研究员,博士。 

  1991年德国达姆施达特技术大学获博士学位,1991年至1999年先后在德国卢卑克医科大学博士后,新西兰奥克兰大学研究员,美国纽约大学受研究助理教授,美国强生公司损伤修复技术中心研究员。200012月至今中国科学院上海硅酸盐所研究员。 

  国际生物材料学会联合会会士(Fellow),英国皇家化学会会士(Fellow),美国医学与生物工程院会士(Fellow),国际可注射骨和关节生物材料学会副主席,国家自然基金委医学部第三/四届专家咨询委员会委员,中国生物材料学会常务理事。全国外科植入物和矫形器械标准化技术委员会组织工程医疗器械产品分技委委员。国际学术期刊“材料化学B”(Journal of Materials Chemistry B)副主编, Biomaterials编委 

  研究领域:组织再生与损伤修复材料(包括硬组织和多种软组织如骨、牙、皮肤、软骨、肌腱、血管、神经、心肌、脂肪、肝脏、肺等),抗菌生物材料,药物缓释材料,以及生物材料与细胞的相互作用(包括对干细胞以及免疫细胞的调控)。主持和完成20多项国家和省部级科研项目,包括中科院“**计划”,国家“973”项目,科技部重点研发计划项目,国家自然基金委重大、重点项目,上海市重大项目,中科院A类先导专项,中科院重要方向性项目,国家自然基金委、中科院、上海市国际合作项目等。 

  在国际学术期刊,包括领域内重要期刊,Materials Today, Advanced Materials, Science Advances, Advanced Functional Materials, Advanced Science, Biomaterials, NanoLetters, Small等发表学术文论400余篇,他引18000余次,英文专著章节11篇,主编英文专著2部,申请国家发明专利91项,国际PCT专利3项,其中55余项已经获得授权。曾获新西兰华人杰出贡献奖(1996年),上海市科技进步二等奖(2006年),第一届长宁区领军人才(2007年),全国归侨侨眷先进个人(2009年),第四届中国侨界贡献奖(创新人才)(2012),中国科学院朱李月华优秀教师奖(2012年),第六届中国侨界贡献奖(创新团队)(2016),中国生物材料学会科学技术一等奖(2019)。 

    

  代表性论文: 

  1. Zhaowenbin Zhang, Qiuxia Dai, Yu Zhang, Hui Zhuang, Endian Wang, Qing Xu, Lingling Ma, Chengtie Wu, Zhiguang Huan, Feng Guo,* and Jiang Chang*, Design of a Multifunctional Biomaterial Inspired by Ancient Chinese Medicine for Hair Regeneration in Burned Skin, ACS Appl. Mater. Interfaces 2020, 12, 12489-12499. 
  2. Lingling Ma, Yanling Zhou, Zhaowenbin Zhang, Yaqin Liu, Dong Zhai, Hui Zhuang, Qin Li, Jianding Yuye, Chengtie Wu, Jiang Chang*. Multi-functional Bioactive Nd-Ca-Si Glasses for Fluorescent Thermometry, Photothermal Therapy and Burn Tissue Repair. Science Advances 2020, ln Press  
  3. Qing Xu, Mengling Chang, Yu Zhang, Endian Wang, Min Xing, Long Gao, Zhiguang Huan, Feng Guo, Jiang Chang*. PDA/Cu bioactive hydrogel with “hot ions effect” for inhibition of drug-resistant bacteria and enhancement of infectious skin wound healing. ACS Applied Materials & Interfaces 2020, ln Press 
  4. Feng Bao, Ge Pei, Zhongcao Wu, Hui Zhuang, Zhaowenbin Zhang, Zhiguang Huan, Chengtie Wu and Jiang Chang*, Bioactive self-pumping composite wound dressings with micropore array modified Janus membrane for enhanced diabetic wound healing, Advanced Fanctional Materials, 2020, in press. 
  5. Yanling Zhou, Chengtie Wu, Jiang Chang*, Bioceramics to regulate stem cells and their microenvironment for tissue regeneration, Materials Today, 2019 (20), 41-56. 
  6. Yu Zhang, Mengling Chang, Feng Bao, Min Xing, Endian Wang, Qing Xu, Zhiguang Huan, Feng Guo* and Jiang Chang*, Multifunctional Zn doped hollow mesoporous silica/polycaprolactone electrospun membranes with enhanced hair follicle regeneration and antibacterial activity for wound healing, Nanoscale, 2019, 11, 6315–6333 
  7. Hongshi Ma,# Quan Zhou,# Jiang Chang, Chengtie Wu*. Grape Seed-Inspired Smart Hydrogel Scaffolds for Melanoma Therapy and Wound Healing. ACS Nano 2019,13(4):4302-4311. 
  8. Tian Li, Dong Zhai, Bing Ma, Jianmin Xue, Pengyu Zhao, Jiang Chang, Michael Gelinsky, Chengtie Wu*.3D Printing of Hot Dog-Like Biomaterials with Hierarchical Architecture and Distinct Bioactivity. Advanced Science 2019, 1901146 (1-8). 
  9. Lei Chen#, Cuijun Deng#, Jiayi Li, Qingqiang Yao*, Jiang Chang*, Liming Wang, Chengtie Wu*.3D printing of a lithium-calcium-silicate crystal bioscaffold with dual bioactivities for osteochondral interface reconstruction. Biomaterials 2019196:138-150. 
  10. Min Yi#, Hekai Li#, Xiaoya Wang, Jianyun Yan, Long Gao, Yinyan He, Xinglong Zhong, Yanbin Cai, Weijing Feng, Zhanpeng Wen, Chengtie Wu, Caiwen Ou*, Jiang Chang*, Minsheng Chen*. Ion Therapy: A Novel Strategy for Acute Myocardial Infarction. Advanced Science. 2019,6(1):1801260 (1-17). 
  11. Chen Yang, Cancan Zhao, Xiaoya Wang, Mengchao Shi, Yanlun Zhu, Linguo Jing, Chengtie Wu, Jiang Chang*. Stimulation of Osteogenesis and Angiogenesis by Micro/Nano Hierarchical Hydroxyapatite via Macrophage Immunomodulation. Nanoscale. 2019,11:17699–17708. 
  12. Long Gao, Yanling Zhou, Jinliang Peng, Chen Xu, Qing Xu, Min Xing, Jiang Chang*. A Novel Dual-adhesive and Bioactive Hydrogel Activated by Bioglass for Wound Healing. NPG Asia Materials 2019,11661-11 
  13. Chen Xu, Bing Ma, Jinliang Peng, Long Gao, Yuhong Xu, Zhiguang Huan, Jiang Chang*. Tricalcium silicate/graphene oxide bone cement with photothermal properties for tumor ablation. Journal of Materials Chemistry B. 2019, 7:2808-2818.  
  14. Yanlun Zhu#, Lingzhi Kong#, Fatemeh Farhadi, Wei Xia, Jiang Chang, Yaohua He*, Haiyan Li*. An injectable continuous stratified structurally and functionally biomimetic construct for enhancing osteochondral regeneration. Biomaterials 2019, 192:149–158. 
  15. Xiaoya Wang, Long Gao, Yan Han, Min Xing, Cancan Zhao, Jinliang Peng, and Jiang Chang*, Silicon-Enhanced Adipogenesis and Angiogenesis for Vascularized Adipose Tissue Engineering, Advanced Science. 2018,1800776 
  16. Yu Zhang, Cui Huang,* and Jiang Chang,* Ca-doped mesoporous SiO2/dental resin composites with enhanced mechanical properties, bioactivity and antibacterial properties, Journal of Materials Chemistry B 2018, 6:477-486   
  17. Yan Huang #, Chengtie Wu #, Xiaoling Zhang, Jiang Chang* Kerong Dai*. Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration. Acta Biomaterialia 2018, 66:81-92. 
  18. Yang Zhou, Yanling Zhou, Long Gao, Chengtie Wu, Jiang Chang*, Synthesis of artificial dental enamel by an elastin-like polypeptide assisted biomimetic approach. Journal of Materials Chemistry B. 2018,6:844-853 
  19. Chen Xu, XiaoYa Wang, Jie Zhou, Zhiguang Huan*, Jiang Chang*, Bioactive tricalcium silicate/alginate composite bone cements with enhanced physicochemical properties. Journal of Biomedical Materials Research: Part B - Applied Biomaterials, 2018, 106B:237-244 
  20. Yanling Zhou, Chen Xua, Xiaoya Wang, Yuandong Dou, Zhiguang Huan*, Jiang Chang*, Fast setting tricalcium silicate/magnesium phosphate premixed cement for root canal filling. Ceramics International. 2018,44:3015-3023 
  21. Chen Yang, Zhiguang Huan, Xiaoya Wang, Chengtie Wu, Jiang Chang*. 3D Printed Fe Scaffolds with HA Nanocoating for Bone Regeneration. ACS Biomaterials Science & Engineering. 2018,4:608-616 
  22. Cancan Zhao, Xiaoya Wang, Long Gao, Linguo Jing, Quan Zhou, Jiang Chang*. The role of the micro-pattern and nano-topography of hydroxyapatite bioceramics on stimulating osteogenic differentiation of mesenchymal stem cells. Acta Biomaterialia 2018,73: 509–521 
  23. Min Xing, Xiaoya Wang, Endian Wang, Long Gao, Jiang Chang*. Bone tissue engineering strategy based on the synergistic effects of silicon and strontium ions. Acta Biomaterialia 2018, 72: 381–395 
  24. Yanling Zhou, Long Gao, Jinliang Peng, Min Xing, Yan Han, Xiaoya Wang, Yuhong Xu, Jiang Chang*. Bioglass Activated Albumin Hydrogels for Wound Healing. Advanced Healthcare Materials 2018, 1800144   
  25. Shuo Chen, Zhiguang Huan, Lin Zhang*, Jiang Chang*. The clinical application of a silicate-based wound dressing (DermFactor) for wound healing after anal surgery: A randomized study. International Journal of Surgery 2018, 52:229232 
  26. Xiaocheng Wang#, Tao Li#, Hongshi Ma, Dong Zhai, Chuan Jiang, Jiang Chang,* Jinwu Wang,* Chengtie Wu*. A 3D-Printed scaffold with MoS2 nanosheets for tumor therapy and tissue regeneration. NPG Asia Materials 2017,9:376-389 
  27. Chen Yang, Xiaoya Wang, Bing Ma, Zhiguang Huan, Nan Ma, Haibo Zhu, Chengtie Wu, and Jiang Chang*, 3D-printed bioactive Ca3SiO5 bone cement scaffolds with nano surface structure for bone regeneration, ACS Applied Materials & Interfaces 2017,9:5757-5767 
  28. Yachen Xu, Jinliang Peng, Xin Dong, Yuhong Xu, Haiyan Li*, Jiang Chang*.  Combined chemical and structural signals of biomaterials synergistically activates cell-cell communications for improving tissue regeneration. Acta Biomaterialia, 2017,55: 249-261 
  29. Yonghui Li#, Yan Han#, Xiaoya Wang, Jinliang Peng, Yuhong Xu, Jiang Chang*. Multi-functional hydrogels prepared by dualion crosslinking for chronic wound healing. ACS Applied Materials & Interfaces.2017,9(19):16054-16062 
  30. Yan Han#, Yonghui Li#, Qiongyu Zeng, Haiyan Li, Jinliang Peng, Yuhong Xu, Jiang Chang*. Injectable bioactive akermanite/alginate composite hydrogels for in situ skin tissue engineering. Journal of Materials Chemistry B. 2017, 5(18) :3315-3326 
  31. Lunguo Xia, Zhilan Yin, Lixia Mao, Xiuhui Wang, Jiaqiang Liu, Xinquan Jiang, Zhiyuan Zhang, Kaili Lin*, Jiang Chang*, Bing Fang*, Akermanite bioceramics promote osteogenesis, angiogenesis and suppress osteoclastogenesis for osteoporotic bone regeneration, Scientific Reports, 2016 ,6:22005. 
  32. Haiyan Li, Jin He, Hongfei Yu, Colin R Green*, Jiang Chang*, Bioglass promotes wound healing by affecting gap junction connexin 43 mediated endothelial cell behavior, Biomaterials, 2016,84:64-75 
  33. Hongshi Ma, Chuan Jiang, Dong Zhai, Yongxiang Luo, Yu Chen, Fang Lv, Zhengfang Yi, Yuan Deng, Jinwu Wang, Jiang Chang,* Chengtie Wu*. A bifunctional biomaterial with photothermal effect for tumor therapy and bone regeneration. Advanced Functional Materials. 2016,26(8):1197-1208 
  34. Xixi Dong#, Haiyan Li#, Yanling Zhou, Long Ou, Junkai Cao, Jiang Chang*. The stimulation of osteogenic differentiation of embryoid bodies from human induced pluripotent stem cells by akermanite bioceramics. J Mater Chem B, 2016, 4, 2369-2376.  
  35. Fangfang Wang, Dong Zhai, Chengtie Wu*, Jiang Chang*. Multifunctional mesoporous bioactive glass/UCNPs nanocomposites with strong red emission for monitoring drug delivery and stimulating osteogenic differentiation of stem cells. Nano Research 2016, 9(4):1193-1208 
  36. Chengtie Wu,* Lunguo Xia, Pingping Han, Lixia Mao, Jiacheng Wang, Dong Zhai, Bing Fang*, Jiang Chang*, Yin Xiao. Europium (Eu)-containing mesoporous bioactive glass scaffolds for stimulating in vitro and in vivo osteogenesis. ACS Appl Mater Interface 2016,8:11342–11354  
  37. Lunguo Xia, Na Zhang, Xiuhui Wang, Yuning Zhou,  Lixia Mao,  Jiaqiang Liu, Xinquan Jiang,  Zhiyuan Zhang, Jiang Chang,* Kaili Lin*,  Bing Fang*. The synergetic effect of nano-structures and silicon-substitution on the properties of hydroxyapatite scaffolds for bone regeneration. Journal of Materials Chemistry B, 2016, 4:3313-3323 
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